Antenatal Diagnosis and Outcome of 12 Congenital Cystic Adenomatoid Malformation of Lung

Objective To investigate the ultrasonic detection probability, type, prenatal diagnosis, and outcome of congenital cystic adenomatoid malformation of lung （CCAM）. Methods In this retrospective study, all 12 cases which were diagnosed with suspected prenatal CC,4M over the period in the hospital were...

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Bibliographic Details
Published in:Journal of reproduction and contraception 2007-12, Vol.18 (4), p.289-295
Main Authors: LI, Xue-lian, ZHOU, Yu-qing, ZHANG, Jue-hua, YAN, Ying-liu, LI, Xiao-tian
Format: Article
Language:English
Subjects:
congenital cystic adenomatoid malformation of lung
outcome
prenatal diagnosis
type
ultrasonic detection
先天性肺囊畸形
出生前鉴定
超声诊断法
鉴定结果
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Summary:Objective To investigate the ultrasonic detection probability, type, prenatal diagnosis, and outcome of congenital cystic adenomatoid malformation of lung （CCAM）. Methods In this retrospective study, all 12 cases which were diagnosed with suspected prenatal CC,4M over the period in the hospital were analyzed. Information on diagnosis time, types and progression of the lesions during pregnancy, the additional abnormalities, and the outcome of pregnancies were recorded. Results The positive rate of ultrasonic detection of CCAM was about 1.01‰ （1/11 124） before 28 gestation weeks. There were 1 case of type Ⅰ （8%）, 2 cases of type Ⅱ （17%） and 9 cases of type Ⅲ （75%）. Nine pregnancies were terminated and 2 cases were confirmed by pathology. Three neonates were alive and without any symptom now. Conclusions Type Ⅲ is the major type. Ultrasound examination during 20-28 weeks and following up, prenatal consultation, chromosome examination offetus, delivery with a pediatrician standing by, and all suspected neonates being investigated are recommended.
ISSN:1001-7844
DOI:10.1016/S1001-7844(07)60035-2