Biological Evaluation of ChuangYuLing Dressing A Multifunctional Medicine Carrying Biomaterial

The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and...

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Bibliographic Details
Published in:Current medical science 2005, Vol.25 (1), p.72-74
Main Author: 彭锐 郑启新 郝杰 邹阳 程杰
Format: Article
Language:English
Subjects:
Animals
ChuangYuLing
Drugs, Chinese Herbal - administration & dosage
Drugs, Chinese Herbal - toxicity
Gelatin
Guinea Pigs
Occlusive Dressings
Phytotherapy
Rabbits
Salvia miltiorrhiza
Wound Healing - drug effects
中药制剂
伤口愈合
生物学评价
生物材料
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Summary:The safety of Chuangyuling (CYL) dressing-a multifunctional medicine carrying biomaterial was evaluated in order to provide foundation for the application of CYL as material used in the wound healing. The traditional Chinese medicine (TCM) extract solution was compounded with scaffolds (gelatin and Bletilla hyacinthine gum), and then frozen and dried to form spongy and porous material CYL. According to the standard of biological evaluation of medical devices that was instituted by the ministry of health of China , the biological evaluation of CYL dressing was conducted. The results showed that all the contents of biological evaluation test consisting of acute toxicity, skin irritation, sensitization and cytotoxicity met the requirement of standards. It was concluded that the biomaterial carrying TCM (CYL dressing) is safe for application of wound healing.
ISSN:1672-0733
2096-5230
1993-1352
2523-899X
DOI:10.1007/bf02831391