Etiological Study on Cystitis Glandularis Caused by Bacterial Infection

• Published in: Journal of Huazhong University of Science and Technology. Medical sciences 2007-12, Vol.27 (6), p.678-680
• Main Author: 刘晓刚 陈志强 叶童群
• Format: Article
• Language: English
• Subjects: Animals; Cystitis - etiology; Cystitis - microbiology; Cystitis - pathology; Escherichia coli; Escherichia coli Infections - pathology; Female; Rats; Rats, Wistar; Urinary Bladder - microbiology; Urinary Bladder - pathology; Urinary Tract Infections - complications; Urinary Tract Infections - microbiology; Urinary Tract Infections - pathology; 大肠杆菌; 病因学; 细菌感染; 膀胱炎
• ISSN: 1672-0733; 1993-1352
• DOI: 10.1007/s11596-007-0615-y

To study the relationship between bacterial infection and the etiology of cystitis glandularis, 36 female Wistar rats were divided into 3 groups. No intervention was given to the rats in the blank group. NS was infused into the bladder of the rats of the control group, and solution containing E. coil was injected into the bladder of experimental group. Three months later, tissue samples of bladder were collected and observed visually and under light microscope. The results showed that tissues of the blank group were normal＇, one sample in the control group showed Brunn＇s nests and cystitis cystica, and 10 in the experimental group had the change of cystitis glandularis. Compared to the blank and control group, samples in the experimental group showed significant change （P〈0.05）. There were no significant difference between blank group and control group （P〉0.05）. It is concluded that bladder instillation of E. coil can induce cystitis glandularis, which confirms that infection is the cause of cystitis glandularis.