Changes in endolymphatic hydrops visualized by magnetic resonance imaging after sac surgery

• Published in: Journal of Huazhong University of Science and Technology. Medical sciences 2016-10, Vol.36 (5), p.736-740
• Main Authors: Zhang, Yuan, Cui, Yong-hua, Hu, Ying, Mao, Zhong-yao, Wang, Qiu-xia, Pan, Chu, Liu, Ai-guo
• Format: Article
• Language: English
• Subjects: Adult; Aged; Contrast Media - administration & dosage; Endolymphatic Hydrops - diagnostic imaging; Endolymphatic Hydrops - pathology; Endolymphatic Hydrops - surgery; Endolymphatic Sac - diagnostic imaging; Endolymphatic Sac - pathology; Endolymphatic Sac - surgery; Female; Gadolinium - administration & dosage; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Medicine; Medicine & Public Health; Meniere Disease - diagnostic imaging; Meniere Disease - pathology; Meniere Disease - surgery; Middle Aged
• ISSN: 1672-0733; 1993-1352
• DOI: 10.1007/s11596-016-1654-z

The purpose of the study was to observe changes in endolymphatic hydrops by using intratympanic injection of gadolinium and magnetic resonance imaging (MRI) before and after endolymphatic sac surgery in patients with unilateral Meniere’s disease. Thirteen patients with unilateral Meniere’s disease undergoing endolymphatic sac surgery were retrospectively and prospectively analyzed. Three-dimensional fluid-attenuated inversion recovery or three-dimensional real inversion recovery MRI was performed 24 h after an intratympanic injection of gadolinium to grade the presence of endolymphatic hydrops. Among the 13 patients with hydrops confirmed by preoperative MRI, vestibular hydrops had no significant change in all patients; cochlear hydrops became negative in 2 patients, and remained unchanged in the other 11 patients after surgery. Definite vertigo attacks were substantially controlled in one patient and completely controlled in 12 patients during a follow-up period of 8-34 months after surgery. The hearing levels were improved in 3 patients, remained unchanged in 7 patients, and decreased in 3 patients. In conclusion, endolymphatic sac surgery does not always alleviate endolymphatic hydrops in patients with Meniere’s disease. Relief from vertigo cannot always be attributed to the remission of hydrops. A change in hearing levels cannot be explained by hydrops status alone.