Synthesis of water-soluble cystine C60 derivative with catalyst and its active oxygen radical scavenging ability

O6; A novel water-soluble cystine C60 derivative was synthesized in the presence of the catalyst, tetrabutylammonium hydroxide (TBAH). The product was characterized by FT-IR, UV, 1H NMR, 13C NMR, MS and elemental analysis. Furthermore, the that cystine C60 derivative showed an excellent efficiency i...

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Published in:Chinese chemical letters 2007-01, Vol.18 (1), p.51-54
Main Authors: Hu, Zhen, Guan, Wen Chao, Tang, Xiang Ying, Huang, Li Zhen, Xu, Hong
Format: Article
Language:English
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Summary:O6; A novel water-soluble cystine C60 derivative was synthesized in the presence of the catalyst, tetrabutylammonium hydroxide (TBAH). The product was characterized by FT-IR, UV, 1H NMR, 13C NMR, MS and elemental analysis. Furthermore, the that cystine C60 derivative showed an excellent efficiency in eliminating superoxygen anion radical and hydroxyl radical. The 50%inhibition concentration (IC50) for superoxygen anion radical and hydroxyl radical were 0.167 and 0.008 mg/mL, respectively.
ISSN:1001-8417
DOI:10.1016/j.cclet.2006.11.013