An unexpected reaction of cyanothioacetamide: Novel preparation of pyrazolo[3,4- b]-pyridine derivatives under MWI

An unexpected multi-component reaction of cyanothioacetamide with aldehyde and aminopyrazole under MWI was reported. Through this reaction, a series of pyrazolo[3,4- b]-pyridine derivatives was prepared in high yields via simple operational procedure.

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Bibliographic Details
Published in:Chinese chemical letters 2008-06, Vol.19 (6), p.643-646
Main Authors: Fan, Xue Sen, Wang, Xia, Li, Xiao Yan
Format: Article
Language:English
Subjects:
Microwave irradiation
Pyrazolo[3,4- b]-pyridine
Thioacetamide
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Summary:An unexpected multi-component reaction of cyanothioacetamide with aldehyde and aminopyrazole under MWI was reported. Through this reaction, a series of pyrazolo[3,4- b]-pyridine derivatives was prepared in high yields via simple operational procedure.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2008.03.005