Evaluation of lipid peroxidation inhibition and free radical scavenging abilities of 5,6,7-tfimethoxy dihydroflavonols

O6; Four naturally rare 5,6,7-trimethoxy-2,3-cis-dihydroflavonols (3-6) and two 5,6,7-trimethoxy-2,3-trans-dihydroflavonols (7-8) were designed and synthesized. Their antioxidative properties were evaluated by way of examining their scavenging capacities towards DPPH and O_2~(·-) free radicals,as we...

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Published in:中国化学快报（英文版） 2009, Vol.20 (10), p.1187-1190
Main Authors: Ke Xin Huang, Yu Bing Feng, Wei Yao, Lei Xiang Yang, Feng Wang, Hai Bo Li, Su Zeng, Jing Xu Gong, Ming Hui Hu, Yu Zhao, Xiu Mei Wu, Xiao Kun Li, Jia Qu
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container_issue 10
container_start_page 1187
container_title 中国化学快报（英文版）
container_volume 20
creator Ke Xin Huang
Yu Bing Feng
Wei Yao
Lei Xiang Yang
Feng Wang
Hai Bo Li
Su Zeng
Jing Xu Gong
Ming Hui Hu
Yu Zhao
Xiu Mei Wu
Xiao Kun Li
Jia Qu
description O6; Four naturally rare 5,6,7-trimethoxy-2,3-cis-dihydroflavonols (3-6) and two 5,6,7-trimethoxy-2,3-trans-dihydroflavonols (7-8) were designed and synthesized. Their antioxidative properties were evaluated by way of examining their scavenging capacities towards DPPH and O_2~(·-) free radicals,as well as by measuring their inhibitory ability against LPO.Both the 2,3-trans and the 2,3-cis conformers exhibited certain quenching abilities to DPPH and O_2~(·-) radicals,while most of the synthetic dihydroflavonols demonstrated remarkable inhibition to LPO.
doi_str_mv 10.1016/j.cclet.2009.04.026
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title Evaluation of lipid peroxidation inhibition and free radical scavenging abilities of 5,6,7-tfimethoxy dihydroflavonols
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