Design, synthesis and in vitro antibacterial activities of methyl-4-((substituted phenyl) [6 H-indolo (2,3- b)quinoxalin-6-yl]methyl-amino)benzoate derivatives

A series of new methyl-4-((substituted phenyl) [6 H-indolo (2,3- b)quinoxalin-6yl]methylamino)benzoate derivatives have been synthesized and assayed for their antibacterial activity on 9 different bacterial strains. Among the screened compounds 2e– 2g exhibited potent inhibitory activity compared to...

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Bibliographic Details
Published in:Chinese chemical letters 2011-05, Vol.22 (5), p.567-570
Main Authors: Murthy, Yellajyosula Lakshmi Narasimha, Karthikeyan, Nagalakshmi, Boddeti, Govindh, Diwakar, Bhagavathula S., Singh, E. Rajendra
Format: Article
Language:English
Subjects:
Antibacterial activity
Isatin
Mannich base
Schiff base
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Summary:A series of new methyl-4-((substituted phenyl) [6 H-indolo (2,3- b)quinoxalin-6yl]methylamino)benzoate derivatives have been synthesized and assayed for their antibacterial activity on 9 different bacterial strains. Among the screened compounds 2e– 2g exhibited potent inhibitory activity compared to standard drug employed, worth further investigation.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2010.10.055