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A novel approach for synthesis of 3-amino-5-aryl-2,5- dihydropyridazines using onium salt as soluble support

In this work it was presented an application of task specific onium salt as soluble support for the synthesis of 3-amino-5-aryl-2,5- dihydropyridazines. This soluble support is of wide applicability and combines advantages of solid phase synthesis without its limitations with those of solution phase...

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Bibliographic Details
Published in:Chinese chemical letters 2011-07, Vol.22 (7), p.823-826
Main Authors: Gao, Meng, Lu, Cui Fen, Yang, Gui Chun, Chen, Zu Xing
Format: Article
Language:English
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Summary:In this work it was presented an application of task specific onium salt as soluble support for the synthesis of 3-amino-5-aryl-2,5- dihydropyridazines. This soluble support is of wide applicability and combines advantages of solid phase synthesis without its limitations with those of solution phase chemistry. After a simple washing step, products were cleaved from the supports and obtained in good yields.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2010.12.055