Photo-crosslinkable hydrogel and its biological applications

Photo-crosslinkable hydrogels can be easily biofabricated for biological tissue engineering applications, through the exposure to ultraviolet or visible light. [Display omitted] In the past few years, photo-crosslinkable hydrogels have drawn a great attention in tissue engineering applications due t...

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Bibliographic Details
Published in:Chinese chemical letters 2021-05, Vol.32 (5), p.1603-1614
Main Authors: Wang, Yuting, Zhang, Shu, Wang, Jian
Format: Article
Language:English
Subjects:
Biofabrication
Biological application
Biomaterial
Hydrogel
Photo-crosslinkable
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Summary:Photo-crosslinkable hydrogels can be easily biofabricated for biological tissue engineering applications, through the exposure to ultraviolet or visible light. [Display omitted] In the past few years, photo-crosslinkable hydrogels have drawn a great attention in tissue engineering applications due to their high biocompatibility and extracellular matrix (ECM)-like structure. They can be easily biofabricated through exposure of a photosensitive system composed of photo-crosslinkable hydrogels, photo-initiators and other compounds such as cells and therapeutic molecules, to ultraviolet or visible light. With the development of biofabrication methods, many researchers studied the biological applications of photo-crosslinkable hydrogels in tissue engineering, such as vascular, wound dressing and bone engineering. This review highlights the biomaterials for photo-crosslinkable hydrogels, biofabrication techniques and their biological applications in tissue engineering. Meanwhile, the challenges and prospects of photo-crosslinkable hydrogels are discussed as well.
ISSN:1001-8417
1878-5964
DOI:10.1016/j.cclet.2020.11.073