Safety of convalescent sera for the treatment of viral severe acute respiratory syndrome： an experimental model in rhesus macaque

Serotherapy has assumed different clinical roles over the years.With the development of antibiotics,the use of serotherapy to treat bacterial diseases declined.However,interest in viral serotherapy increased due to the lack of a specific therapy for viral infections.Human convalescent sera have been...

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Bibliographic Details
Published in:Chinese medical journal 2013, Vol.126 (19), p.3790-3792
Main Authors: He, Wei-ping, Li, Bo-an, Zhao, Jun, Cheng, Yun
Format: Article
Language:English
Subjects:
Animals
Disease Models, Animal
Immunization, Passive - methods
Lung - pathology
Macaca mulatta
Severe Acute Respiratory Syndrome - blood
Severe Acute Respiratory Syndrome - pathology
Severe Acute Respiratory Syndrome - therapy
呼吸系统综合症
安全性
实验模型
恢复期
治疗
猕猴
痘病毒感染
血清
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Summary:Serotherapy has assumed different clinical roles over the years.With the development of antibiotics,the use of serotherapy to treat bacterial diseases declined.However,interest in viral serotherapy increased due to the lack of a specific therapy for viral infections.Human convalescent sera have been used to treat and prevent measles,mumps,polio,Spanish flu,vaccinia and varicella viral infection,among others.
ISSN:0366-6999
2542-5641
DOI:10.3760/cma.j.issn.0366-6999.20130958