Role of Combining Spreading Moxibustion and Point Injection in Reducing ECP and LPO Levels and Improving Lung Function

• Published in: Journal of acupuncture and tuina science 2014-02, Vol.12 (1), p.12-16
• Main Authors: Xu, Jing, Zheng, Su, Fang, Wei
• Format: Article
• Language: English
• Subjects: Acupuncture; Asthma; Clinical Study; Medicine; Medicine & Public Health
• ISSN: 1672-3597; 1993-0399
• DOI: 10.1007/s11726-014-0739-0

Objective： To observe the effect of combining spreading moxibustion and point injection on serum eosinophil cationic protein（ECP）, lipid peroxidase（LPO） and cellular immunity in patients with cough-variant asthma. Methods： A total of 150 cases who met the inclusion criteria were randomized into three groups, 50 in each group. Spreading moxibustion and point injection were employed in the observation group, spreading moxibustion alone in the spreading moxibustion group and point injection alone in the point injection group. Then the therapeutic efficacies were evaluated after one course of treatment. Results： The recovery rate and total effective rate were 50.0% and 98.0% respectively in the observation group, versus 18.0% and 86.0% in the spreading moxibustion group and 14.0% and 82.0% in the point injection group, showing a statistically significant difference（P 〈 0.01）. Before treatment, there were no inter-group statistically significant differences in levels of ECP, LPO, CD3＋,CD4＋, CD4＋/CD8＋ and CD8＋, forced vital capacity（FCV）, forced expiratory volume 1（FEV1）, and peak expiratory flow（PEF）（P〉0.05）. After treatment, the ECP and LPO levels in the observation group were more significantly reduced than those in the other two groups, showing statistically significant difference（P〈0.01）; the levels of CD3＋, CD4＋ and CD4＋/CD8＋ in the observation group were significantly elevated but CD8＋ was significantly reduced, showing statistically significant differences compared with those in the other two groups（P〈0.01）; and the lung function indexes（FVC, FEV1 and PEF） in the observation group were more significantly elevated than those in the other two groups（P〈0.05）. Conclusion： Combining spreading moxibustion and point injection could remarkably reduce the contents of ECP and LPO in patients with cough-variant asthma, improve cellular immunity, increase the contents of CD3＋, CD4＋ and CD4＋/CD8＋, reduce the content of CD8＋ and improve the lung function.