Rigid, Self‐Assembled Hydrogel Composed of a Modified Aromatic Dipeptide

A simple dipeptide self‐assembles into a biocompatible hydrogel (see figure and inside cover). This novel biomaterial is extremely simple to prepare and has a remarkable rigidity. It is very stable under extreme conditions, can be injected, and can be shaped according to the vessel it has been assem...

Full description

Saved in:
Bibliographic Details
Published in:Advanced materials (Weinheim) 2006-06, Vol.18 (11), p.1365-1370
Main Authors: Mahler, A., Reches, M., Rechter, M., Cohen, S., Gazit, E.
Format: Article
Language:English
Subjects:
Biomaterials
Biomedical materials
Hydrogels
Peptides
Self‐assembly
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A simple dipeptide self‐assembles into a biocompatible hydrogel (see figure and inside cover). This novel biomaterial is extremely simple to prepare and has a remarkable rigidity. It is very stable under extreme conditions, can be injected, and can be shaped according to the vessel it has been assembled in. The hydrogel allows a wide variety of possible biomedical applications including tissue engineering, axonal regeneration, and controlled drug release.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.200501765