Cover Picture: Heterochromia in Designed Metallopeptides: Geometry-Selective Binding of CdII in a De Novo Peptide (Angew. Chem. Int. Ed. 35/2007)

Heterochromia is a genetic condition that causes individuals to have eyes of different colors. In the same way, nearly identical metal‐binding sites in heterochromic peptides, an example of which is presented by V. L. Pecoraro and co‐workers in their Communication on page 6688 ff., display different...

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Bibliographic Details
Published in:Angewandte Chemie International Edition 2007-09, Vol.46 (35), p.6559-6559
Main Authors: Iranzo, Olga, Cabello, Chris, Pecoraro, Vincent L.
Format: Article
Language:English
Subjects:
cadmium
coordination modes
de novo peptides
metalloproteins
protein design
Online Access:Get full text
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Summary:Heterochromia is a genetic condition that causes individuals to have eyes of different colors. In the same way, nearly identical metal‐binding sites in heterochromic peptides, an example of which is presented by V. L. Pecoraro and co‐workers in their Communication on page 6688 ff., display different physical properties after metal binding. The cover picture shows a de novo designed heterochromic peptide that binds two CdII ions, each with a different coordination geometry.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200790171