Front Cover: Fluorocarbon‐DNA Conjugates for Enhanced Cellular Delivery: Formation of a Densely Packed DNA Nano‐Assembly (ChemBioChem 19/2024)

Several RF‐DNA conjugates are synthesized, and the relationship between the uptake efficiency and the physicochemical properties is systematically investigated. RF‐DNA conjugates carrying two C8F17 groups at the terminus of a DNA strand form a nano‐assembly with the highest DNA content, leading to t...

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Bibliographic Details
Published in:Chembiochem : a European journal of chemical biology 2024-10, Vol.25 (19), p.n/a
Main Authors: Narita, Minako, Kohata, Ai, Kageyama, Taiichi, Watanabe, Honoka, Aikawa, Kohsuke, Kawaguchi, Daisuke, Morihiro, Kunihiko, Okamoto, Akimitsu, Okazoe, Takashi
Format: Article
Language:English
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Summary:Several RF‐DNA conjugates are synthesized, and the relationship between the uptake efficiency and the physicochemical properties is systematically investigated. RF‐DNA conjugates carrying two C8F17 groups at the terminus of a DNA strand form a nano‐assembly with the highest DNA content, leading to the greatest cellular uptake via scavenger receptors. More details can be found in article 10.1002/cbic.202400436 by Ai Kohata, Kohsuke Aikawa, and co‐workers.
ISSN:1439-4227
1439-7633
DOI:10.1002/cbic.202481901