Cauliflower‐like NiCo2O4−Zn/Al Layered Double Hydroxide Nanocomposite as an Efficient Electrochemical Sensing Platform for Selective Pyridoxine Detection

• Published in: Electroanalysis (New York, N.Y.) N.Y.), 2020-06, Vol.32 (6), p.1160-1169
• Main Authors: Amini, Roghayeh, Asadpour‐Zeynali, Karim
• Format: Article
• Language: English
• Subjects: Cauliflower-like; Layered double hydroxide; Metal oxide; NiCo2O4; Vitamin B6
• ISSN: 1040-0397; 1521-4109
• DOI: 10.1002/elan.201900600

In the present study, a cauliflower‐like NiCo2O4−Zn/Al CO32- layered double hydroxide (NiCo2O4−Zn/Al LDH) nanocomposite was used as a novel electrode material for the sensitive and selective determination of pyridoxine (vitamin B6). The structure and morphology of the as‐prepared nanocomposite were characterized by X‐ray diffraction (XRD), FT‐IR, field emission scanning electron microscopy (FESEM) and energy dispersive X‐ray spectroscopy (EDX). The NiCo2O4−Zn/Al LDH nanocomposite exhibited excellent electrocatalytic ability in the oxidation of pyridoxine, which could result from the synergistic effect of the two components. The developed sensor also provided a selective determination of pyridoxine in the presence of other species such as vitamins (B1, B2, B12 and ascorbic acid), inorganic ions and biomolecules. The fabricated sensor showed a good linear response for pyridoxine over the concentration ranges 2×10−7–2.0×10−4 mol L−1 with a low detection limit of 8.6×10−8 mol L−1. Finally, the proposed method was successfully applied for the determination of pyridoxine in commercial tablets and plasma samples with satisfactory results. Furthermore, this novel sensor displayed superior benefits in terms of stability, sensitivity, repeatability and cost. The present work aims to expand NiCo2O4 based nanocomposites to sensor fields and promote the development of pyridoxine sensors.