Determination of Buprenorphine (BUP) with Molecularly Imprinted Polymer Zn/La3+ Metal Organic Framework on Modified Glassy Carbon Electrode (GCE)

• Published in: Electroanalysis (New York, N.Y.) N.Y.), 2022-06, Vol.34 (6), p.1012-1020
• Main Authors: Yahyapour, Moghadaseh, Ranjbar, Mehdi, Mohadesi, Alireza, Rejaeinegad, Moslem
• Format: Article
• Language: English
• Subjects: Buprenorphine; Glassy carbon electrode; Microwave method; Sensor; Zn/La3
• ISSN: 1040-0397; 1521-4109
• DOI: 10.1002/elan.202100266

In this study we report the Zn/La3+ metal organic frameworks (MOFs) were synthesized with the co‐precipitation assisted microwave method. Zn/La3+ MOFs were used as a new nanocomposite for the design and construction of a nanosensor based on glassy carbon electrode (GCE). MOFs due to their unique and excellent physicochemical properties can be used in sensors based on glassy carbon electrode (GCE). The synergistic effect of MOFs on glassy carbon electrode increases the power of the limits of detection (LOD). In this study, a new chemical sensor was fabricated by electro polymerization to measure buprenorphine with MOFs based on molecularly imprinted polymer. Zn/La3+ MOFs nanostructures were identified with scanning electron microscopy (SEM), Dynamic light scattering (DLS), Transmission electron microscopy (TEM) and the Fourier‐transform infrared spectroscopy (FT‐IR) spectra. Buprenorphine was used as a template, pyrrole was used as a monomer, potassium ferrocyanide as an electrochemical active tracer in electropolymerization processes and the parameters affecting the sensor response were optimized. At the Zn/La3+ MOF/MIP electrode, the calibration curve in the linear region was obtained in the concentration range between 4 to 50 ng/ml and the detection limit was 1.08 ng/ml. In a new strategy, Zn/La3+ MOFs nanostructures can be introduced as new materials with high efficiency which used at chemical sensors for detection of the opiates in all over the world.