Quick and easy preparation method for decoctions of kampo formula (part 3): Extraction efficiency of the IPCD method for volatile compounds

ABSTRACT Aim The immersing powdered crude drugs (IPCD) method was developed as a quick, easy and high‐yield way to prepare decoctions. IPCD may be very useful for decoctions of crude drugs containing volatile compounds because it does not involve boiling. The aim of this study was therefore to test...

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Published in:Traditional & Kampo medicine 2016-10, Vol.3 (2), p.157-161
Main Authors: Fueki, Tsukasa, Sumino, Megumi, Makino, Toshiaki, Matsuoka, Takanori, Beppu, Masashi, Tanaka, Koichiro, Namiki, Takao
Format: Article
Language:English
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decoction
immersing powdered crude drug
volatile compound
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container_end_page 161
container_issue 2
container_start_page 157
container_title Traditional & Kampo medicine
container_volume 3
creator Fueki, Tsukasa
Sumino, Megumi
Makino, Toshiaki
Matsuoka, Takanori
Beppu, Masashi
Tanaka, Koichiro
Namiki, Takao
description ABSTRACT Aim The immersing powdered crude drugs (IPCD) method was developed as a quick, easy and high‐yield way to prepare decoctions. IPCD may be very useful for decoctions of crude drugs containing volatile compounds because it does not involve boiling. The aim of this study was therefore to test this hypothesis using cinnamon bark (the bark of the trunk of Cinnamomum cassia) and perilla herb (the leaves and the tips of the branches of Perilla frutescens var. acuta). Methods The amounts of the marker compounds in the IPCD immersion prepared from cinnamon bark or perilla herb were measured and compared with those prepared with the conventional decoction method. Results The amounts of cinnamaldehyde and perillaldehyde in the IPCD immersion per 1 g of crude drugs exceeded those in the conventional decoctions by two‐fold and 30‐fold, respectively. Conclusion The IPCD method is outstanding for the decoction of crude drugs containing volatile compounds.
doi_str_mv 10.1002/tkm2.1044
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IPCD may be very useful for decoctions of crude drugs containing volatile compounds because it does not involve boiling. The aim of this study was therefore to test this hypothesis using cinnamon bark (the bark of the trunk of Cinnamomum cassia) and perilla herb (the leaves and the tips of the branches of Perilla frutescens var. acuta). Methods The amounts of the marker compounds in the IPCD immersion prepared from cinnamon bark or perilla herb were measured and compared with those prepared with the conventional decoction method. Results The amounts of cinnamaldehyde and perillaldehyde in the IPCD immersion per 1 g of crude drugs exceeded those in the conventional decoctions by two‐fold and 30‐fold, respectively. 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IPCD may be very useful for decoctions of crude drugs containing volatile compounds because it does not involve boiling. The aim of this study was therefore to test this hypothesis using cinnamon bark (the bark of the trunk of Cinnamomum cassia) and perilla herb (the leaves and the tips of the branches of Perilla frutescens var. acuta). Methods The amounts of the marker compounds in the IPCD immersion prepared from cinnamon bark or perilla herb were measured and compared with those prepared with the conventional decoction method. Results The amounts of cinnamaldehyde and perillaldehyde in the IPCD immersion per 1 g of crude drugs exceeded those in the conventional decoctions by two‐fold and 30‐fold, respectively. 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immersing powdered crude drug
volatile compound
title Quick and easy preparation method for decoctions of kampo formula (part 3): Extraction efficiency of the IPCD method for volatile compounds
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