Synthesis of several 2‐carbaldehyde derivatives of quinoline and 1,4‐dihydroquinoline

Quinolines represent a versatile class of compounds known for their antimalarial potential. The quinoline derivatives are the class of truly ubiquitous structures involved in the regulation of a wide variety of biological processes. In this paper, several quinoline‐2‐carbaldehyde and 1,4‐dihydroquin...

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Bibliographic Details
Published in:Vietnam journal of chemistry 2020-06, Vol.58 (3), p.309-313
Main Authors: Chinh, Pham The, Tham, Pham Thi, Van Tuyen, Nguyen, Quynh, Duong Huong, Van, Dinh Thuy, Bang, Duong Nghia, Kien, Vu Tuan, Giang, Bui Duong, Thuy, Nguyen Thi, Nhan, Bui Thanh, Giang, Luu Truong
Format: Article
Language:English
Subjects:
Biological
Carbaldehyde
Heterocyclic
Quinoline
Riley reaction
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Summary:Quinolines represent a versatile class of compounds known for their antimalarial potential. The quinoline derivatives are the class of truly ubiquitous structures involved in the regulation of a wide variety of biological processes. In this paper, several quinoline‐2‐carbaldehyde and 1,4‐dihydroquinoline‐2‐carbaldehyde derivatives were synthesized via Riley reaction. These valuable organic compounds are unique precursors for the synthesis of new plinabulin and new heterocyclic compounds containing ring system of quinolines.
ISSN:0866-7144
2572-8288
2572-8288
DOI:10.1002/vjch.2019000166