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Herrmananes A and B, two new sulfated hydrocarbons from the sea cumber Stichopus herrmanni
Using various chromatographic separations, two new sulfated hydrocarbons namely herrmananes A and B (1 and 2) were isolated from the aqueous fraction of the methanol residue of the sea cucumber Stichopus herrmanni. Their chemical structures were elucidated by extensive analysis of the 1D, 2D NMR and...
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Published in: | Vietnam journal of chemistry 2022-10, Vol.60 (5), p.685-687 |
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container_title | Vietnam journal of chemistry |
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creator | Vien, Le Thi Hanh, Tran Thi Hong Quang, Tran Hong Van Thanh, Nguyen Cuong, Nguyen Xuan Nam, Nguyen Hoai |
description | Using various chromatographic separations, two new sulfated hydrocarbons namely herrmananes A and B (1 and 2) were isolated from the aqueous fraction of the methanol residue of the sea cucumber Stichopus herrmanni. Their chemical structures were elucidated by extensive analysis of the 1D, 2D NMR and HR‐QTOF mass spectra. In addition, compound 1 showed significant cytotoxicity on SK‐Mel‐2 cell line with IC50 value of 23.12 ± 1.87 μM, whereas 2 exhibited moderate effect on this cell line with IC50 value of 55.28 ± 4.17 μM. |
doi_str_mv | 10.1002/vjch.202200095 |
format | article |
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subjects | cytotoxic activity Sea cucumber Stichopus herrmanni sulfated hydrocarbon |
title | Herrmananes A and B, two new sulfated hydrocarbons from the sea cumber Stichopus herrmanni |
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