Dosimetry of the I-Plant Model 3500 iodine-125 brachytherapy source

125 I brachytherapy sources have been widely used for interstitial implants for a number of years in several tumor sites, especially the prostate. The design of the new I-Plant Model 3500 iodine source is novel, yet its characteristics are similar to those of two existing designs, Model 6711 and the...

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Bibliographic Details
Published in:Medical physics (Lancaster) 2001-04, Vol.28 (4), p.661-670
Main Authors: Duggan, D. M., Johnson, B. L.
Format: Article
Language:English
Subjects:
125I
Anisotropy
brachytherapy
Brachytherapy - instrumentation
Brachytherapy - methods
Cancer
dosimetry
iodine
Iodine Radioisotopes
Models, Statistical
Monte Carlo Method
Numerical modeling
Phantoms, Imaging
Photons
Physicists
radiation therapy
radioactive sources
radioisotopes
Radiometry
Solid hydrogen
Task Group 43
Temperature
Therapeutic applications, including brachytherapy
Thermoluminescent dosimeters
Water
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Description
Summary:125 I brachytherapy sources have been widely used for interstitial implants for a number of years in several tumor sites, especially the prostate. The design of the new I-Plant Model 3500 iodine source is novel, yet its characteristics are similar to those of two existing designs, Model 6711 and the Symmetra. Dosimetry parameters (including dose rate constant, radial dose function, and anisotropy function, as defined by AAPM Task Group 43) were measured with LiF thermoluminescent dosimeters in water-equivalent plastic phantoms. The dose rate constant was found by direct comparison of calibrated I-Plant Model 3500 and Model 6711 seeds in a solid water phantom, to be 1.01 (cGy/h)/U. The radial dose function and anisotropy function are similar to those of the Model 6711 and Symmetra seeds.
ISSN:0094-2405
2473-4209
DOI:10.1118/1.1357456