Abstract 10737: Does the Evidence Support a Radial Approach in Non-ST Elevation Acute Coronary Syndromes?

• Published in: Circulation (New York, N.Y.) N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A10737-A10737
• Main Authors: Amaduzzi, Peter L, Cenko, Edina, Kedev, Sasko, Kalpak, Oliver, Stankovic, Goran, Vasiljevic, Zorana, Vavlukis, Marija, Scarpone, Marialuisa, Rajabi, Monireh, Pavasovic, Sasa, Manfrini, Olivia, Milicic, Davor, Koller, Akos, Badimon, Lina, Bugiardini, Raffaele
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539

IntroductionTrans-radial access (TRA) for PCI has been consistently shown to reduce mortality and bleeding complications compared with trans-femoral access (TFA) in pts with STEMI. On the contrary the efficacy and the safety of TRA in NSTE-ACS is still matter of debateHypothesisThe purpose of this study was to determine the potential clinical benefits of TRA in the NSTE-ACS patient populationMethodsWe compared outcomes of TRA versus TFA in a real world population of patients with NSTE-ACS drawn from the ISACS-TC registry (NCT01218776) The primary outcome was the incidence of all cause death and stroke at 30 days. The secondary outcome was the combined endpoint of periprocedural major complications (MI type 4, abrupt closure, loss of side branches, distal embolization and postPCI TIMI flow≤2). The incidence of nonCABG related major bleeding (TIMI definition) was also notedResultsOf 3127 NSTE ACS patients undergoing PCI 2047 (65.5%) underwent TRA, which was more likely to be employed among male sex and patients with lower-risk characteristicspatients were younger with a lower burden of risk factors. Patients undergoing TRA had significantly more periprocedural complications than those who received TFA (24.4% vs 8.6% p