Abstract 11988: Exercise-Induced Hypoxia Can Predict Hypobaric Hypoxia During Flight in Patients After the Fontan Operation

IntroductionMild but significant hypoxia characterizes the Fontan circulation which may be vulnerable to hypobaric condition during air travel.MethodsWe prospectively evaluated arterial oxygen saturation (SpO2;%) (PULSOX-Me300) (hypobaric hypoxia) during flight in stable 10 Fontan patients (male=4,...

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Published in:Circulation (New York, N.Y.) N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A11988-A11988
Main Authors: Morimoto, Yoshihito, Ohuchi, Hideo, Toyoshima, Yuka, Miike, Hikari, Negishi, Jun, Iwasa, Toru, Sakaguchi, Heima, Kurosaki, Kenichi
Format: Article
Language:English
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Summary:IntroductionMild but significant hypoxia characterizes the Fontan circulation which may be vulnerable to hypobaric condition during air travel.MethodsWe prospectively evaluated arterial oxygen saturation (SpO2;%) (PULSOX-Me300) (hypobaric hypoxia) during flight in stable 10 Fontan patients (male=4, aged 15 to 35) and 8 healthy volunteers (Controlmale=4, aged 30 to 36). SpO2was measured before taking off (S1), at the initial (S2) and the end of stabilization (S3) and after landing (S4). Associations of the SpO2-dynamics were compared with SpO2-dynamics during cardiopulmonary exercise testing (CPX) and hemodynamics in Fontan.ResultsSpO2at S1, S2, S3, and S4 was 92±3, 87±5, 86±5, and 91±3 for Fontan, and 97±1, 93±2, 94±2, and 97±1 for Control. SpO2at all phases were lower in the Fontan (p
ISSN:0009-7322
1524-4539