Abstract 15309: Prevalence, Predictors, and Outcomes of Patients With Tachycardia-Related Cardiomyopathy Due to Atrial Fibrillation

• Published in: Circulation (New York, N.Y.) N.Y.), 2018-11, Vol.138 (Suppl_1 Suppl 1), p.A15309-A15309
• Main Authors: Techawantochandej, Athittaya, Lee, Hon-Chi, Gersh, Bernard J, Wysokinski, Waldemar E, Patlolla, Sri Harsha, Greene, Eddie L, Oh, Jae K, Melduni, Rowlens M
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539

IntroductionTachycardia-induced cardiomyopathy (TICM) is a potentially reversible condition characterized by left ventricular (LV) dilatation and systolic dysfunction mediated by tachyarrhythmias. This study sought to determine the prevalence and long-term outcomes of patients with TICM in a community-based cohort of patients with incident atrial fibrillation (AF).MethodsThe Olmsted County, MN AF database was queried to identify patients with incident AF 1980-2010 who had normal ejection fraction (EF ≥50%) at baseline, and EF assessment at time of AF diagnosis (0-7 days) and at follow-up (7-90 days) (N=928). TICM diagnosis was based a reduction in EF ≥15% from baseline at AF diagnosis, in the absence of recent surgery, acute MI, obstructive CAD, active myocarditis or pericarditis. Multivariate regression analysis was used to identify the independent factors associated with TICM (logistic) and mortality (Cox).ResultsA total of 908 patients met inclusion criteria. The prevalence of TICM was 8.5%. At AF diagnosis, patients with TICM had lower EF (36.5±8.1 vs 61.0±7.0, p