Abstract 13143: Time Course and Outcomes of Major Bleeding Events According to Bleeding Site in Patients Receiving Anticoagulant Therapy for Venous Thromboembolism

BackgroundBleeding is the most feared complication of anticoagulant therapy in patients with venous thromboembolism (VTE). Limited data exist about patient characteristics, time course and outcomes of major bleeding, according to the bleeding site.MethodsWe used the data from the Registro Informatiz...

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Published in:Circulation (New York, N.Y.) N.Y.), 2019-11, Vol.140 (Suppl_1 Suppl 1), p.A13143-A13143
Main Authors: Bikdeli, Behnood, Moustafa, Fares, Nieto, José Antonio, Lee, Alfred I, Ruíz-Giménez, Nuria, Lorenzo, Alicia, Schellong, Sebastian M, Soler, Silvia, Morales, Maria Del Valle, Bosevski, Marijan, Gavín, Olga, Lip, Gregory, Monreal, Manuel
Format: Article
Language:English
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Summary:BackgroundBleeding is the most feared complication of anticoagulant therapy in patients with venous thromboembolism (VTE). Limited data exist about patient characteristics, time course and outcomes of major bleeding, according to the bleeding site.MethodsWe used the data from the Registro Informatizado Enfermedad TromboEmbólica (RIETE) registry (03/2001-07/2018), and identified patients who suffered from major bleeding during anticoagulation. We assessed patient characteristics, time course, and 30-day outcomes (mortality, re-bleeding, and VTE recurrences), according to bleeding site.ResultsAmong 78,136 patients with VTE receiving anticoagulation, 2,244 (2.9%) suffered from major bleeding (gastrointestinal in 800, intracranial in 417, hematoma in 410, genitourinary in 222, retroperitoneal in 145; other sites in 250). There were variations in baseline characteristics, including older age (P
ISSN:0009-7322
1524-4539
DOI:10.1161/circ.140.suppl_1.13143