Abstract 15153: Association of Life’s Simple 7 With Nonsustained Ventricular Tachycardia: The Atherosclerosis Risk in Communities Study

• Published in: Circulation (New York, N.Y.) N.Y.), 2019-11, Vol.140 (Suppl_1 Suppl 1), p.A15153-A15153
• Main Authors: Krishnappa, Darshan, Wang, Wendy, Norby, Faye L, Zhang, Michael J, Kim, Jonathan, Oldenburg, Niki C, Soliman, Elsayed Z, Roukoz, Henri, Adkisson, Wayne O, Alonso, Alvaro, Lutsey, Pamela L, Chen, Lin Yee
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.140.suppl_1.15153

IntroductionNonsustained ventricular tachycardia (NSVT) is associated with an increased risk of mortality and heart failure hospitalization. Although suboptimal lifestyle risk factors are associated with higher atrial fibrillation (AF) risk, it is unknown whether they are associated with NSVT. In this study, we examined the relationship of Life’s Simple 7 score (LS7) and individual LS7 factors to the presence of NSVT in late-life in the Atherosclerosis Risk in Communities (ARIC) Study.MethodsWe assessed LS7 factors for 2223 participants at Visit 3 (V3, 1993-95), and a composite score from 0-14 was calculated. At V6 (2016-17), a 2-week continuous heart rhythm monitor (Zio XT Patch) was applied and NSVT (yes/no) was defined as a wide complex tachycardia ≥ 4 beats with a rate >120 beats/minute. Logistic regression was used to evaluate the association of LS7 score and individual factors at V3 with odds of NSVT at V6.ResultsThe participants were aged 57.9 ± 5 years at V3 and 78.8 ± 4 years at V6, 57.9% were females and 18.9% were black. The mean recording time of the Zio XT Patch was 12.6 ± 2.6 days. Of these participants, 656 participants (29.5%) had NSVT on the Zio XT Patch monitor. The mean LS7 score was 8.7 ± 2.1. There was no significant association between LS7 score at V3 and presence of NSVT at V6. Additionally, none of the individual LS7 factors at V3 showed a significant association with occurrence of NSVT at V6 (Table).ConclusionWhile lifestyle risk factors play a critical etiological role in AF, they appear to be less important for NSVT. Although an upstream approach of lifestyle modification may be effective in reducing the risk of AF, this approach per se may not prevent NSVT. Further research is needed to identify critical risk factors for NSVT to refine risk stratification and prevention strategies.