Abstract 15303: Performance of the HAS-BLED, ATRIA, and PRECISE-DAPT Bleeding Risk Scores in Atrial Fibrillation Patients Using Antiplatelet Agents or Oral Anticoagulants

• Published in: Circulation (New York, N.Y.) N.Y.), 2019-11, Vol.140 (Suppl_1 Suppl 1), p.A15303-A15303
• Main Authors: Kim, Moo Hyun, Choi, Sun Young, Lee, Kwang Min, Song, Kai, Cho, Young-Rak, Park, Jong Sung, Park, Kyungil, Jang, Chanhee
• Format: Article
• Language: English
• ISSN: 0009-7322; 1524-4539
• DOI: 10.1161/circ.140.suppl_1.15303

BackgroundVarious bleeding risk scores have been proposed to assess the risk of bleeding in atrial fibrillation (AF) patients undergoing anticoagulation. PRECISE DAPT score has been developed to assess the out-of hospital bleeding risk in patients receiving dual antiplatelet therapy. Our objective was to compare the predictive performance between the HAS-BLED, ATRIA and PRECISE-DAPT score in AF patients using antiplatelet agents or anticoagulantsMethodsWe recruited 1,114 consecutive AF patients (51% male; median age, 71 years) receiving antiplatelet agents or oral anticoagulants from January 2014 through December 2018. Major bleeding was defined as according to the Bleeding Academic Research Consortium (BARC) criteria (type 3 or 5hemodynamic instability, need for transfusion, drop in hemoglobin ≥ 3 g, and intracranial, intraocular or fatal bleeding). The performance of risk scores were assessed by C-statistic.ResultsBleeding events occurred in 135 patients (12.1%) during 30 days, and 72 patients (6.5%) from 30 days till 1-year follow-up. Based on the C-statistic, PRECISE-DAPT score (AUC0.72, 95% CI0.69-0.75) had a good performance, significantly better than HAS-BLED (AUC0.64, 95% CI0.61-0.67) (p = 0.008) or ATRIA scores (AUC0.57, 95% CI0.54-0.60) (p < 0.001) for 30-days bleeding prediction. Also, PRECISE-DAPT score had a good C-statistic (AUC0.72, 95% CI0.69-0.75) for 1-year bleeding events compared with HAS-BLED (AUC0.64, 95% CI0.60-0.67) (p=0.02) or ATRIA (AUC0.61, 95% CI0.58-0.65) (p=0.01).ConclusionsThe PRECISE-DAPT score has been used for assessing bleeding events. Also, the PRECISE-DAPT score predicted bleedings better than HAS-BLED or ATRIA scores in AF patients. So, the PRECISE-DAPT score may be considered as bleeding risk score during DAPT or oral anticoagulation in clinical practice.