Abstract 10402: H2FPEF Score as a Prognostic Tool to Predict Mortality and Hospitalization in Adults with Normal Left Ventricular Ejection Fraction and Dyspnea: A Systematic Review and Meta-Analysis

• Published in: Circulation (New York, N.Y.) N.Y.), 2021-11, Vol.144 (Suppl_1), p.A10402-A10402
• Main Authors: Del Rio-Pertuz, Gaspar, Triana, Abel, correa, jose, Rios, Jackie, Abohelwa, Mostafa, Parmar, Kanak, Elmassry, Mohamed, Argueta-Sosa, Erwin E
• Format: Article
• Language: English
• ISSN: 0009-7322
• DOI: 10.1161/circ.144.suppl_1.10402

IntroductionThe score “H2FPEF’’ has been described as a tool to predict heart Failure with Preserved Ejection fraction (HFpEF). The scoring criteria and interpretation are as follows0 or 1, exclude HFpEF; 2-5, further examination is needed to confirm the diagnosis; and 6-9, high probability of HFpEF diagnosis. However, predicting the prognosis of patients by using this scoring system is an ongoing topic of interest. HypothesisH2FPEF score can be used to predict mortality and heart failure (HF) hospitalization in adults with normal left ventricular ejection fraction (LVEF) and dyspnea. MethodsWe systematically searched Pubmed, Embase, and Scopus for abstracts and full-text articles from inception to May 2021. Studies were included if they evaluated the relationship between a high H2FPEF score (defined as ≥6) and mortality or hospitalization due to HF in adults with normal LVEF and/or dyspnea. Pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated using the random-effects model by DerSimonian and Laird. ResultsA total of 4 studies were included that had a total of 8071 patients (mean age72 years, 49% were females) with an overall mortality of 35%. The relationship between a high H2FPEF score between survivors and non-survivors demonstrated an association with mortality (OR:1.73 CI:1.41-2.11 p