Influence of different rehabilitative aerobic exercise programs on (anti-) inflammatory immune signalling, cognitive and functional capacity in persons with MS – study protocol of a randomized controlled trial

Background Studies have shown positive effects of therapeutic exercise on motor- and cognitive function as well as on psychosocial outcomes in persons with multiple sclerosis (MS). A reduction of inflammatory stress through physical exercise has been suspected as one key mechanism, mediating the pos...

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Bibliographic Details
Published in:BMC neurology 2019-03, Vol.19 (1), p.37-9, Article 37
Main Authors: Joisten, Niklas, Rademacher, Annette, Bloch, Wilhelm, Schenk, Alexander, Oberste, Max, Dalgas, Ulrik, Langdon, Dawn, Caminada, Daniel, Purde, Mette-Triin, Gonzenbach, Roman, Kool, Jan, Zimmer, Philipp, Bansi, Jens
Format: Article
Language:English
Subjects:
Activities of Daily Living
Adult
Aerobic capacity
Aerobic exercises
Aerobics
Anti-inflammatory agents
Biological markers
Biomarkers - blood
Care and treatment
Chronic effects
Chronic illnesses
Clinical trials
Cognition
Cognitive ability
Cytokines
Cytokines - blood
Demyelinating diseases
Diabetes
Disease
Exercise
Exercise therapy
Exercise Therapy - methods
Exercise Tolerance
Fatigue
Fatigue - etiology
Fatigue - prevention & control
Health aspects
Heart rate
Helper cells
High-intensity interval exercise
High-Intensity Interval Training
Humans
Immune response
Immune signalling
Immune system
Inflammation
Information processing
Lymphocytes T
Medical care quality
Medicine
Medicine & Public Health
Mental depression
Metabolites
Multiple sclerosis
Multiple Sclerosis, Chronic Progressive - immunology
Multiple Sclerosis, Chronic Progressive - psychology
Multiple Sclerosis, Chronic Progressive - rehabilitation
Multiple Sclerosis, Relapsing-Remitting - immunology
Multiple Sclerosis, Relapsing-Remitting - psychology
Multiple Sclerosis, Relapsing-Remitting - rehabilitation
Neurochemistry
Neurology
Neurosurgery
Neurotoxicity
Patient outcomes
Physical fitness
Physical therapy
Physical training
Psychological aspects
Quality of Life
Randomized Controlled Trials as Topic
Recurrence (Disease)
Rehabilitation
Single-Blind Method
Studies
Study Protocol
T cells
T-Lymphocytes, Regulatory - metabolism
Th17 Cells - metabolism
Time Factors
Treatment Outcome
Tryptophan
Tryptophan - blood
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