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Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia
Elevated levels of cardiovascular disease (CVD) risk markers are highly prevalent in people with a spinal cord injury (SCI). Breaking up prolonged sedentary time with short, regular bouts of physical activity can reduce postprandial glucose and lipid levels in able‐bodied individuals. The effects in...
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| Main Authors: | , , , , , , , |
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| Format: | Default Article |
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2020
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| Online Access: | https://hdl.handle.net/2134/12058875.v1 |
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| author | Daniel Bailey Thomas Withers Vicky Goosey-Tolfrey David Dunstan Christof Leicht Rachael Champion Opie Charlett Louise Ferrandino |
| author_facet | Daniel Bailey Thomas Withers Vicky Goosey-Tolfrey David Dunstan Christof Leicht Rachael Champion Opie Charlett Louise Ferrandino |
| author_sort | Daniel Bailey (7040024) |
| collection | Figshare |
| description | Elevated levels of cardiovascular disease (CVD) risk markers are highly prevalent in people with a spinal cord injury (SCI). Breaking up prolonged sedentary time with short, regular bouts of physical activity can reduce postprandial glucose and lipid levels in able‐bodied individuals. The effects in people with paraplegia are unknown. The study aims were to examine the acute postprandial glucose (primary aim), lipid, blood pressure, and psychological responses (secondary aims) to breaking up prolonged sedentary time in individuals with paraplegia. This was a randomized crossover design trial. Fourteen participants with paraplegia (age 51 ± 9 years, trunk fat mass 44.3 ± 7.7%) took part in the following two, 5.5‐hour conditions: (1) uninterrupted sedentary time (SED), and (2) sedentary time interrupted with 2 minutes of moderate‐intensity arm crank ergometer physical activity every 20 minutes (SED‐ACT). Standardized breakfast and lunch test meals were consumed during each condition. The outcomes were compared between conditions using linear mixed models. Glucose area under the curve (AUC) was significantly lower during the lunch postprandial period in SED‐ACT vs SED (incremental AUC 1.9 [95% CI 1.0, 2.7) and 3.0 [2.1, 3.9] mmol/L∙2.5 hour, respectively, P = .015, f = 0.34). There were no differences between conditions for the breakfast or total 5.5 hours postprandial periods (P > .05). Positive affect was higher in SED‐ACT than SED (P = .001). Breaking up prolonged sedentary time acutely attenuates lunch postprandial glucose and improves positive affect in people with paraplegia. This may have clinical relevance for reducing CVD risk and improving psychological well‐being in this population. |
| format | Default Article |
| id | rr-article-12058875 |
| institution | Loughborough University |
| publishDate | 2020 |
| record_format | Figshare |
| spelling | rr-article-120588752020-04-21T00:00:00Z Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia Daniel Bailey (7040024) Thomas Withers (8654385) Vicky Goosey-Tolfrey (1256892) David Dunstan (3436484) Christof Leicht (1254333) Rachael Champion (8654391) Opie Charlett (8654394) Louise Ferrandino (8960906) Sport Sciences Human Movement and Sports Sciences physical activity exercise spinal cord injury sedentary behaviour activity breaks cardiometabolic health wellbeing Elevated levels of cardiovascular disease (CVD) risk markers are highly prevalent in people with a spinal cord injury (SCI). Breaking up prolonged sedentary time with short, regular bouts of physical activity can reduce postprandial glucose and lipid levels in able‐bodied individuals. The effects in people with paraplegia are unknown. The study aims were to examine the acute postprandial glucose (primary aim), lipid, blood pressure, and psychological responses (secondary aims) to breaking up prolonged sedentary time in individuals with paraplegia. This was a randomized crossover design trial. Fourteen participants with paraplegia (age 51 ± 9 years, trunk fat mass 44.3 ± 7.7%) took part in the following two, 5.5‐hour conditions: (1) uninterrupted sedentary time (SED), and (2) sedentary time interrupted with 2 minutes of moderate‐intensity arm crank ergometer physical activity every 20 minutes (SED‐ACT). Standardized breakfast and lunch test meals were consumed during each condition. The outcomes were compared between conditions using linear mixed models. Glucose area under the curve (AUC) was significantly lower during the lunch postprandial period in SED‐ACT vs SED (incremental AUC 1.9 [95% CI 1.0, 2.7) and 3.0 [2.1, 3.9] mmol/L∙2.5 hour, respectively, P = .015, f = 0.34). There were no differences between conditions for the breakfast or total 5.5 hours postprandial periods (P > .05). Positive affect was higher in SED‐ACT than SED (P = .001). Breaking up prolonged sedentary time acutely attenuates lunch postprandial glucose and improves positive affect in people with paraplegia. This may have clinical relevance for reducing CVD risk and improving psychological well‐being in this population.<br> 2020-04-21T00:00:00Z Text Journal contribution 2134/12058875.v1 https://figshare.com/articles/journal_contribution/Acute_effects_of_breaking_up_prolonged_sedentary_time_on_cardiovascular_disease_risk_markers_in_adults_with_paraplegia/12058875 CC BY 4.0 |
| spellingShingle | Sport Sciences Human Movement and Sports Sciences physical activity exercise spinal cord injury sedentary behaviour activity breaks cardiometabolic health wellbeing Daniel Bailey Thomas Withers Vicky Goosey-Tolfrey David Dunstan Christof Leicht Rachael Champion Opie Charlett Louise Ferrandino Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia |
| title | Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia |
| title_full | Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia |
| title_fullStr | Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia |
| title_full_unstemmed | Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia |
| title_short | Acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia |
| title_sort | acute effects of breaking up prolonged sedentary time on cardiovascular disease risk markers in adults with paraplegia |
| topic | Sport Sciences Human Movement and Sports Sciences physical activity exercise spinal cord injury sedentary behaviour activity breaks cardiometabolic health wellbeing |
| url | https://hdl.handle.net/2134/12058875.v1 |