Dimethyl sulfoxide: a central player since the dawn of cryobiology, is efficacy balanced by toxicity?

Dimethyl sulfoxide (DMSO) is the cryoprotectant of choice for most animal cell systems since the early history of cryopreservation. It has been used for decades in many thousands of cell transplants. These treatments would not have taken place without suitable sources of DMSO that enabled stable and...

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Bibliographic Details
Main Authors: Maooz Awan, Iryna Buriak, Roland Fleck, Barry Fuller, Anatoliy Goltsev, Julie Kerby, Mark Lowdell, Pavel Mericka, Alexander Petrenko, Yuri Petrenko, Olena Rogulska, Alexandra Stolzing, Glyn N Stacey
Format: Default Article
Published: 2020
Subjects:
cell therapy
cell therapy safety
cryobiology
cryopreservation
cryoprotectants
cryoprotectant toxicity
dimethyl sulfoxide
DMSO toxicity
Online Access:https://hdl.handle.net/2134/12284297.v1
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