4,4,16‐Trifluoropalmitate: design, synthesis, tritiation, radiofluorination and pre‐clinical PET imaging studies on myocardial fatty acid oxidation

Fatty acid oxidation (FAO) produces the majority of ATP used to sustain the cardiac contractile work, while glycolysis is a secondary source of ATP under normal physiological conditions. FAO impairment has been reported in the advanced stages of Heart Failure (HF) and is strongly linked to disease p...

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Bibliographic Details
Main Authors: Matteo Zanda, Alessandro Colombano, Sergio Dall'Angelo, Lee Kingston, Gunnar Grönberg, Claudia Correia, Rossana Passannante, Zuriñe Baz, Miguel Angel Morcillo, Charles Elmore, Jordi Llop
Format: Default Article
Published: 2020
Subjects:
Organic chemistry not elsewhere classified
PET imaging
Fatty acids
Radiopharmaceuticals
Heart failure
Palmitate
Organic Chemistry
Online Access:https://hdl.handle.net/2134/12925397.v1
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https://hdl.handle.net/2134/12925397.v1

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