Tuning morphology in active pharmaceutical ingredients: controlling the crystal habit of lovastatin through solvent choice and non-size-matched polymer additives

Additive crystallization routes to control the crystal habit of the active pharmaceutical ingredient (API) lovastatin are presented, at small scale up to 25 mL. Lovastatin is an archetypical example of an API that forms needle-like crystals via solution-based recrystallization, causing issues for do...

Full description

Bibliographic Details

Main Authors:	Lauren E Hatcher, Wei Li, Pollyanna Payne, Brahim Benyahia, Chris Rielly, Chick C Wilson
Format:	Default Article
Published:	2020
Subjects:	Inorganic chemistry not elsewhere classified Inorganic & Nuclear Chemistry Physical Chemistry (incl. Structural) Materials Engineering Inorganic Chemistry
Online Access:	https://hdl.handle.net/2134/12977585.v1
Tags:	Add Tag No Tags, Be the first to tag this record!