Mechanical loading of tissue engineered skeletal muscle prevents dexamethasone induced myotube atrophy

Skeletal muscle atrophy as a consequence of acute and chronic illness, immobilisation, muscular dystrophies and aging, leads to severe muscle weakness, inactivity and increased mortality. Mechanical loading is thought to be the primary driver for skeletal muscle hypertrophy, however the extent to wh...

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Bibliographic Details
Main Authors: Kathryn Aguilar-Agon, Andrew Capel, Jacob Fleming, Darren J. Player, Neil Martin, Mark Lewis
Format: Default Article
Published: 2020
Subjects:
Animal physiology - biophysics
Animal physiology - cell
Animal physiology - systems
Dexamethasone
C2C12
Hypertrophy
Skeletal muscle
Myotubes
Ubiquitin-proteasome
Ubiquitin–proteasome
Physiology
Online Access:https://hdl.handle.net/2134/13102376.v2
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https://hdl.handle.net/2134/13102376.v2

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