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CFTR limits F-actin formation and promotes morphological alignment with flow in human lung microvascular endothelial cells

Micro- and macrovascular endothelial dysfunction in response to shear stress has been observed in cystic fibrosis (CF), and has been associated with inflammation and oxidative stress. We tested the hypothesis that the cystic fibrosis transmembrane conductance regulator (CFTR) regulates endothelial a...

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Bibliographic Details
Main Authors: Adam J Causer, Maha Khalaf, Emily Klein Rot, Kimberly Brand, James Smith, Stephen Bailey, Michael H Cummings, Anthony I Shepherd, Zoe L Saynor, Janis K Shute
Format: Default Article
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/2134/17105741.v1
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