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Potential of microneedle systems for COVID-19 vaccination: current trends and challenges

To prevent the coronavirus disease 2019 (COVID-19) pandemic and aid the restoration to pre-pandemic normality, a global mass vaccination is urgently needed. Inducing herd immunity through mass vaccination has proven to be a highly effective strategy for preventing the spread of many infectious disea...

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Main Authors: Jasmin Hassan, Charlotte Haigh, Tanvir Ahmed, Md Jasim Uddin, Diganta Das
Format: Default Article
Published: 2022
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Online Access:https://hdl.handle.net/2134/19731988.v1
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author Jasmin Hassan
Charlotte Haigh
Tanvir Ahmed
Md Jasim Uddin
Diganta Das
author_facet Jasmin Hassan
Charlotte Haigh
Tanvir Ahmed
Md Jasim Uddin
Diganta Das
author_sort Jasmin Hassan (12518077)
collection Figshare
description To prevent the coronavirus disease 2019 (COVID-19) pandemic and aid the restoration to pre-pandemic normality, a global mass vaccination is urgently needed. Inducing herd immunity through mass vaccination has proven to be a highly effective strategy for preventing the spread of many infectious diseases, which protect the most vulnerable population groups that are unable to develop immunity, such as people with immunodeficiencies or weakened immune systems due to underlying medical or debilitating conditions. To have a global outreach, the maintenance of the vaccine potency, transportation, needle waste generation becomes a major issue. Moreover, needle phobia and vaccine hesitancy acts as a hurdle for successful mass vaccination. The use of dissolvable microneedles for the COVID-19 vaccination could act as a major paradigm shift in attaining the desired goal to vaccinate billions in the shortest time possible. In addressing these points, we discuss the potential of the use of dissolvable microneedles for COVID-19 vaccination based on the current literature.
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institution Loughborough University
publishDate 2022
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spelling rr-article-197319882022-05-16T00:00:00Z Potential of microneedle systems for COVID-19 vaccination: current trends and challenges Jasmin Hassan (12518077) Charlotte Haigh (12518080) Tanvir Ahmed (224986) Md Jasim Uddin (5434142) Diganta Das (1254000) COVID-19 vaccine delivery Dissolvable microneedles Immunogenicity Mass vaccination <p>To prevent the coronavirus disease 2019 (COVID-19) pandemic and aid the restoration to pre-pandemic normality, a global mass vaccination is urgently needed. Inducing herd immunity through mass vaccination has proven to be a highly effective strategy for preventing the spread of many infectious diseases, which protect the most vulnerable population groups that are unable to develop immunity, such as people with immunodeficiencies or weakened immune systems due to underlying medical or debilitating conditions. To have a global outreach, the maintenance of the vaccine potency, transportation, needle waste generation becomes a major issue. Moreover, needle phobia and vaccine hesitancy acts as a hurdle for successful mass vaccination. The use of dissolvable microneedles for the COVID-19 vaccination could act as a major paradigm shift in attaining the desired goal to vaccinate billions in the shortest time possible. In addressing these points, we discuss the potential of the use of dissolvable microneedles for COVID-19 vaccination based on the current literature.</p> 2022-05-16T00:00:00Z Text Journal contribution 2134/19731988.v1 https://figshare.com/articles/journal_contribution/Potential_of_microneedle_systems_for_COVID-19_vaccination_current_trends_and_challenges/19731988 CC BY 4.0
spellingShingle COVID-19 vaccine delivery
Dissolvable microneedles
Immunogenicity
Mass vaccination
Jasmin Hassan
Charlotte Haigh
Tanvir Ahmed
Md Jasim Uddin
Diganta Das
Potential of microneedle systems for COVID-19 vaccination: current trends and challenges
title Potential of microneedle systems for COVID-19 vaccination: current trends and challenges
title_full Potential of microneedle systems for COVID-19 vaccination: current trends and challenges
title_fullStr Potential of microneedle systems for COVID-19 vaccination: current trends and challenges
title_full_unstemmed Potential of microneedle systems for COVID-19 vaccination: current trends and challenges
title_short Potential of microneedle systems for COVID-19 vaccination: current trends and challenges
title_sort potential of microneedle systems for covid-19 vaccination: current trends and challenges
topic COVID-19 vaccine delivery
Dissolvable microneedles
Immunogenicity
Mass vaccination
url https://hdl.handle.net/2134/19731988.v1