Developing a process control strategy for the consistent and scalable manufacture of human mesenchymal stem cells

Human mesenchymal stem cells (hMSCs) have been identified as a promising cell-based therapy candidate to treat a number of unmet clinical indications, however, in vitro expansion will be required to increase the available number of cells and meet this demand. Scalable manufacturing processes, amenab...

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Bibliographic Details
Main Author: Thomas R.J. Heathman
Format: Default Thesis
Published: 2015
Subjects:
Chemical engineering not elsewhere classified
Cell-based therapy
Consistency
Cryopreservation
Downstream process development
Human mesenchymal stem cell
Manufacture
Microcarrier
Process control
Regenerative medicine
Serum-free
Chemical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/22174
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https://hdl.handle.net/2134/22174

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