A potentially scalable method for the harvesting of hMSCs from microcarriers

The use of hMSCs for allogeneic therapies requiring lot sizes of billions of cells will necessitate large-scale culture techniques such as the expansion of cells on microcarriers in bioreactors. Whilst much research investigating hMSC culture on microcarriers has focused on growth, much less involve...

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Bibliographic Details
Main Authors: Alvin W. Nienow, Qasim Rafiq, Karen Coopman, Christopher Hewitt
Format: Default Article
Published: 2014
Subjects:
Chemical engineering not elsewhere classified
Human mesenchymal stem cells
Microcarriers
Large scale processing
Downstream processing
Cell harvest
Agitation
Chemical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/14883
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