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Oxaliplatin complexes with carnosine and its derivatives: in vitro cytotoxicity, mass spectrometric and computational studies with a focus on complex fragmentation

The complexation of the Pt-based anti-cancer drug oxaliplatin (OxPt) with biological ligands other than DNA is believed to be a major cellular sink for the drug reducing its therapeutic potential and acting as a potential cause of toxicity. In this paper, an in vitro study on hepatocellular carcinom...

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Bibliographic Details
Main Authors: Eslam M. Moustafa, Claire L. Camp, Ahmed S. Youssef, Asma Amleh, Helen Reid, Barry Sharp, Tamer Shoeib
Format: Default Article
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/2134/16071
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