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Synthesis and reactions of cyclopropamitosenes and related pyrrolo[1,2-a]indoles
The use of Mitomycin C in the treatment of a wide range of neoplastic conditions is discussed. The mechanism of action of mitomycin anticancer antibiotics under reductive activation conditions using either enzymes, sodium dithionite, catalytic hydrogenation or chromium (Il) perchlorate is examined,...
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| Format: | Default Thesis |
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1992
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| Online Access: | https://hdl.handle.net/2134/14132 |
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