Prevention of rejection of allogeneic endothelial cells in a biohybrid lung by silencing HLA-class I expression

Variability in Human Leukocyte Antigens (HLA) remains a hurdle to the application of allogeneic cellular products. Due to insufficient autologous endothelial cell harvesting for the biohybrid lung, allogeneic human cord blood derived endothelial cells (HCBEC) were used for the endothelialization of...

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Bibliographic Details
Main Authors: Bettina Wiegmann, Constanca Figueiredo, Christiane Gras, Michael Pflaum, Sabrina Schmeckebier, Sotiris Korossis, Axel Haverich, Rainer Blasczyk
Format: Default Article
Published: 2014
Subjects:
Mechanical engineering not elsewhere classified
Biohybrid lung
HLA
Biomaterial
Endothelial cells
Mechanical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/37198
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