Tocopherol-mediated modulation of age-related changes in microglial cells: Turnover of extracellular oxidized protein material

Proteins accumulate during aging and form insoluble protein aggregates. Microglia are responsible for their removal from the brain. During aging, changes within the microglia might play a crucial role in the malfunctioning of these cells. Therefore, we isolated primary microglial cells from adult ra...

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Bibliographic Details
Main Authors: Alexandra Stolzing, Rebecca Widmer, Tobias Jung, Peter Voss, Tilman Grune
Format: Default Article
Published: 2006
Subjects:
Mechanical engineering not elsewhere classified
Aging
CD36
Microglia
Oxidized proteins
Protein degradation
Vitamin E
Mechanical Engineering not elsewhere classified
Online Access:https://hdl.handle.net/2134/16869
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https://hdl.handle.net/2134/16869

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