Tribology of rough ultra-film contacts in drug delivery devices

Elastomeric seals are extensively used in an assortment of drug delivery devices, such as syringes and pressurized metered dose inhalers. Although tribology of rubber seals and o-rings is reasonably well understood in engineering applications, the drug mixtures and formulations do not enjoy the requ...

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Bibliographic Details
Main Authors: David W. Grimble, Stephanos Theodossiades, Homer Rahnejat, M. Wilby
Format: Default Article
Published: 2008
Subjects:
Mechanical engineering not elsewhere classified
Pressurized metered dose inhalers
Rough thin-film contact
Asperity interaction
Adhesion
Mechanical Engineering not elsewhere classified
Mechanical Engineering
Online Access:https://hdl.handle.net/2134/4699
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https://hdl.handle.net/2134/4699

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