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Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study

Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multiethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white t...

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Main Authors: Mark Hamer, Roland von Kanel, Manja Reimann, Nico T. Malan, Alta E. Schutte, Hugo W. Huisman, Leone Malan
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Published: 2014
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Online Access:https://hdl.handle.net/2134/19175
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author Mark Hamer
Roland von Kanel
Manja Reimann
Nico T. Malan
Alta E. Schutte
Hugo W. Huisman
Leone Malan
author_facet Mark Hamer
Roland von Kanel
Manja Reimann
Nico T. Malan
Alta E. Schutte
Hugo W. Huisman
Leone Malan
author_sort Mark Hamer (1254141)
collection Figshare
description Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multiethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed heart disease, use of anti-hypertensives, anti-diabetic, or statin medications at either time point) compared to whites (49.1 vs. 32.0%, p ¼ 0.012) respectively. After controlling for baseline, the black participants demonstrated greater increases in 24 h systolic and diastolic blood pressure, total cholesterol, fasting glucose, fibrinogen, D-dimer, and waist circumference in comparison with whites. In summary, an adverse progression of CVD risk factors was observed in the whole sample, although to a larger degree in black participants. Aggressive treatment strategies for controlling risk factors in black Africans are needed to reduce the increasing burden of CVD in South Africa.
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spelling rr-article-96304312014-01-01T00:00:00Z Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study Mark Hamer (1254141) Roland von Kanel (7243703) Manja Reimann (354641) Nico T. Malan (7243715) Alta E. Schutte (7248008) Hugo W. Huisman (7248011) Leone Malan (7242182) Other health sciences not elsewhere classified Black African Biomarkers Cardiovascular disease Epidemiology Medical and Health Sciences not elsewhere classified Recent work identified a high prevalence of modifiable risk factors for cardiovascular disease (CVD) among urban black South Africans. The aim was to track the progression of CVD risk factors in a multiethnic sample of South Africans. Participants were 173 black (aged 47.5 ± 7.8 yrs) and 186 white teachers (aged 49.6 ± 9.9 yrs) that were examined at baseline and 3 years follow-up. Blacks demonstrated a substantially higher prevalence of composite CVD burden (defined as history of physician diagnosed heart disease, use of anti-hypertensives, anti-diabetic, or statin medications at either time point) compared to whites (49.1 vs. 32.0%, p ¼ 0.012) respectively. After controlling for baseline, the black participants demonstrated greater increases in 24 h systolic and diastolic blood pressure, total cholesterol, fasting glucose, fibrinogen, D-dimer, and waist circumference in comparison with whites. In summary, an adverse progression of CVD risk factors was observed in the whole sample, although to a larger degree in black participants. Aggressive treatment strategies for controlling risk factors in black Africans are needed to reduce the increasing burden of CVD in South Africa. 2014-01-01T00:00:00Z Text Journal contribution 2134/19175 https://figshare.com/articles/journal_contribution/Progression_of_cardiovascular_risk_factors_in_black_Africans_3_year_follow_up_of_the_SABPA_cohort_study/9630431 CC BY-NC-SA 4.0
spellingShingle Other health sciences not elsewhere classified
Black African
Biomarkers
Cardiovascular disease
Epidemiology
Medical and Health Sciences not elsewhere classified
Mark Hamer
Roland von Kanel
Manja Reimann
Nico T. Malan
Alta E. Schutte
Hugo W. Huisman
Leone Malan
Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_full Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_fullStr Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_full_unstemmed Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_short Progression of cardiovascular risk factors in black Africans: 3 year follow up of the SABPA cohort study
title_sort progression of cardiovascular risk factors in black africans: 3 year follow up of the sabpa cohort study
topic Other health sciences not elsewhere classified
Black African
Biomarkers
Cardiovascular disease
Epidemiology
Medical and Health Sciences not elsewhere classified
url https://hdl.handle.net/2134/19175