Diels–Alder reactions of heterocyclic fused [alpha]-pyrones by P. Mark Jackson

“…The chemistry of heterocyclic analogues of orthoquinodimethane is reviewed. Benzothieno[2,3-c]pyran-3-ones and the isomeric [3,2-c]pyranones are stable analogues of benzothiophene-2,3-qyinodimethane. …”
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A novel hetero Diels - Alder reaction as a route to annelated pyridines and bipyridines by David A. Riddick

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Research Data for "Solvent-mediated rate deceleration of Diels-Alder reactions for enhanced selectivity: quantum mechanical insights" by Felix Plasser

“…These contain subfolders for the structures as defined within the main article.Each subfolder contains further subfolders:sp: Single point energy calculations for respective structureopt: Geometry optimization calculations for respective structureIn addition to sp and opt 1, 2a and 2d also contain:nbo: Single point energy calculation with natural bonds orbitals analysisFiles in sp and opt folders are:acetone.gjf: Gaussian input file for respective structure in acetoneacetone.log: Gaussian output file for respective structure in acetonegas.gjf: Gaussian input file for respective structure in gas phasegas.log: Gaussian output file for respective structure in gas phasetoluene.gjf: Gaussian input file for respective structure in toluenetoluene.log: Gaussian output file for respective structure in tolueneFiles in nbo folders are:gas_0.gjf: Gaussian input file for respective structure with zero charge in gas phasegas_0.LOG: Gaussian output file for respective structure with zero charge in gas phasegas_+1.gjf: Gaussian input file for respective structure with +1 charge in gas phasegas_+1.LOG: Gaussian output file for respective structure with +1 charge in gas phasegas_-1.gjf: Gaussian input file for respective structure with -1 charge in gas phasegas_-1.LOG: Gaussian output file for respective structure with -1 charge in gas phaseData for calculations performed in n-hexane, diethylether, DCM  and DMSO is present in the folder named extra_solvents. …”
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Studies toward the synthesis of the guaianolide skeleton: an intramolecular hetero Diels Alder approach and a carbonyl ene approach by Giovanni Gambera

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Novel methods for allylic amination by an intramolecular nitroso ene reaction by Duncan Atkinson

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Asymmetric synthesis : approaches via enantiomerically pure acetal and oxazoline ligands by Louise M. Newman

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Data for 'N₂ fixation and cycling in Alnus glutinosa, Betula pendula and Fagus sylvatica woodland exposed to free air CO₂ enrichment' by Jonathan Millett, Douglas Godbold, Andrew Smith, Helen Grant

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Multiple photoluminescence from pyrene-fused hexaarylbenzenes with aggregation enhanced emission features by Chuan-Zeng Wang, Yuki Noda, Chong Wu, Xing Feng, Perumal Venkatesan, Hang Cong, Mark Elsegood, Thomas G. Warwick, Simon J. Teat, Carl Redshaw, Takehiko Yamato

“…Multiple photoluminescence, involved in monomer emission, excimer emission and charge transfer emission origin from new pyrene-fused hexaarylbenzenes (HAB) compounds were observed, which were designed and synthesized (in high yield) via the Diels-Alder reaction of bis(2-tert-butylpyren-6-yl)acetylene and tetraphenylcyclopentadienone. …”
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Studies concerning bridged isoquinolines and related compounds by Angela S. Mallard

“…The reaction between 2,5,6-trichloro-3,4-pyridyne and p-diisopropyl benzene thus led to 1,3,4-trichloro-5,8-dihydro-6,9-diisopropyl-5,8-ethenoisoquinoline but only in 18% yield. …”
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Studies in isoquinoline chemistry relating to morphine analgesics by Michael J. Powell

“…This latter ring closure has been found not to take, place and the former route also did not prove satisfactory. The synthesis of ring-A bridged isoquinolines has been studied. Although thermal isomerisation of 2,5-dihydrophenylacetamides to give conjugated dienes followed by Diels–Alder reaction met with limited success, the Diels–Alder reaction of 1,2,3,4,7,8-hexahydro-6-methoxy-2-methylisoquinoline has been achieved with methyl vinyl ketone, phenyl vinyl ketone and 2-chloroacrylonitrile. …”
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Studies in aryne chemistry by Ian F. Eckhard

“…In addition, tetrafluorobenzyne forms a 5,8-adduct with a 5,7-diene and with a 5,7,9(11)-triene. …”
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The synthesis of novel linked heterocycles by Jason Bloxham

“…Chapter 1 reviews the literature with regard to the synthesiS of substituted carbazoles via the cyc\oaddition reactions of indole-2,3-quinodimethanes and its equivalents with dienophiles. …”
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The reactions of codeinone and hydroxycodeinone by Mohammad U. Valhari

“…Derivatives of Diels-Alder adducts of thebaine and of 14-hydroxy codeinone provide some of the most potent analgesics in the morphine-thebaine group of alkaloids. …”
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Synthesis of new codeinone and indolinocodeinone derivatives by R.M. Allen

“…As an extension to the range of available compounds the preparation of modified thebaines and 14-N-substituted codeinones was a desirable objective. …”
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Synthetic approaches towards novel indole alkaloids by Edward B. Fray

“…Section 2.2 describes the study of stable analogues of indole-2,3-quinodimethane and the Dials–Alder reactions thereof. …”
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Synthesis and electrochemical properties of the naturally occurring free radical scavenger carazostatin by P. Mark Jackson, Christopher J. Moody, Roger J. Mortimer

“…A short synthesis of the naturally occurring free radical scavenger carazostatin 1 starting from indol-3-ylacetic acid is described, the key step being the regiospecific Diels–Alder reaction of the indolopyrone 2 with ethyl trimethylsilylpropynoate. …”
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Some studies in the chemistry of reactive intermediates by Ram P. Sharma

“…The reactions of tetrafluorobenzyne with 2-methyl- and 2,5-dimethylfuran gave the expected Diels–Alder adducts (dihydro-tetrafluoroepoxinaphthalene derivatives) which on treatment with butadiene afforded 9-methyl- and 9,10-dimethyltetrahydrotetrafluoroanthracenes. …”
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End group removal and modification of RAFT polymers by Helen Willcock, Rachel K. O'Reilly

“…The lability of the thiocarbonylthio group, which facilitates the RAFT mechanism, allows for ready post-polymerisation functionalisation of RAFT polymers by a number of techniques. In particular, end group thermolysis, radical induced reduction, hetero-Diels-Alder reactions and reaction with nucleophiles are discussed as are the applications and limitations of each method. …”
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Synthetic approach to the novel cholecystokinin (CCK)-B receptor antagonist tetronothiodin by Kevin J. Batchelor

“…The introduction includes the initial ideas for the construction of this subunit, with analogous subunits in the literature being discussed. A brief review of the likely chemistry is discussed. …”
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The room-temperature stabilization of bicyclo[2.2.2]oct-1-ene and bicyclo[3.2.1]oct-1-ene by Paul Roach, Ralf Warmuth

“…Retardation through incarceration: The highly strained anti-Bredt bridgehead olefin bicyclo[2.2.2]oct-1-ene (1) is remarkably stable at 60 °C, if generated photochemically inside the hemicarcerand 2. …”
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The synthesis of potential analgesics derived from thebaine by Michael Burton

“…These are the α- and β-1,2,4-triazines (4 and 5), the 1,2,4-triazol-5-thione (6) and the 1,3,4-oxadiazole (7). …”
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Novel synthetic applications of N-acyliminium ions toward β-turn mimetics and naturally occurring alkaloids by Sean N. Gaskell

“…The application of this novel methodology in target synthesis has been demonstrated by the manipulation of chiral building blocks such as (3). The removal of functional groups has allowed assess to therapeutically active natural products including (+)-crispine A (4) and (+)-harmicine (5), whilst the exploitation of their existing functionality has been utilized to form complex β-turn peptide mimics, such as (6). …”
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The reactions of thebaine with C-nitroso-compounds by Peter Horsewood

“…Evidence for the existence and structure of nitrosyl cyanide was investigated further by undertaking a study of its reactions with other conjugated dienes to give N-cyano-1,2-oxazines. …”
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Synthetic approaches to tremorgenic indoles by Carrie-Ann Harrison

“…To this end, studies on the preparation of a trans-fused hydrindane system and its incorporation into the central indole moiety are discussed in Chapter 2. …”
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The synthesis of Diarylisobenzofuran and Adamantylidene probes for the selective detection of singlet oxygen in plasma by James Fuster

“…The mechanistic understanding of singlet oxygen is limited due to its short lifetime (14 μs in ethanol). The research in this thesis showed that the highest concentration of singlet oxygen produced in plasma (150 V) was achieved using a 0.75% admixture of oxygen. …”
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Enzymatic fluorination of biotin and tetrazine conjugates for pretargeting approaches to positron emission tomography imaging by Phillip T. Lowe, Sergio Dall'Angelo, Andrew Devine, Matteo Zanda, David O'Hagan

“…This study reports the fluorinase-mediated transhalogenation [5′-chloro-5′-deoxyadenosine (ClDA) substrates to 5′-fluoro-5′-deoxyadenosine (FDA) products] of two antibody pretargeting tools, a FDA-PEG-tetrazine and a [18F]FDA-PEG-biotin, and each is assessed either for its compatibility towards iEDDA ligation to trans-cyclooctene or for its affinity to avidin. …”
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Approaches towards the synthesis of the natural product phorbol by Darren Davies

“…The role of protein kinase C in the wide variety of biological responses demonstrated by the phorbol esters has also been discussed. …”
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The restoration of former opencast mining land to woodland : development and evaluation of a GIS-based tool for strategic planting and management by Janette Lee

“…Given the spatial nature of these problems, there is scope for GIS to be used as a tool to meet this need. The issue of land restoration following opencast mineral extraction is considered. …”
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Studies in the chemistry of benzobicyclo systems by Steven V. Ley

“…Thus, for example, 1-N, N-dimethylamino-tetrafluorobenzobarrelene gives 2,3,4,5- tetrafluoro-k'-N, N-dimethylaminobiphenyl in high yield and 1,2,3,1- tetrafluoro-5,8-dihydro-5,8-N-(-methyl)-iminonaphthalene affords 2'- (2,3,4,5-tetrafluorophenyl)-N-methyl. pyrrole. …”
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Design, synthesis, conjugation and reactivity of novel trans,trans-1,5-cyclooctadiene-derived bioorthogonal linkers by Beatrice Longo, Chiara Zanato, Monica Piras, Sergio Dall'Angelo, Albert D Windhorst, Danielle Vugts, Massimiliano Baldassarre, Matteo Zanda

“…This two-step strategy relies on the use of new bifunctional TCO linkers (5a–11a) for IEDDA reactions, which can be synthesized via 1,3-dipolar cycloaddition of (E,E)-COD 1 with different azido spacers (5–11) carrying an electrophilic function (NHS-ester, N-succinimidyl carbonate, p-nitrophenyl-carbonate, maleimide) in the ω-position. …”
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Ion mobility-mass spectrometry studies of organic and organometallic complexes and reaction monitoring by Victoria E. Wright

“…Ion mobility-mass spectrometry (IM-MS) has the capability of separating ions based on m/z, size and shape, providing additional structural information compared to using mass spectrometry on its own. …”
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