Search Results - Parkinson, G. A.~

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    A new class of fluorinated A2A adenosine receptor agonist with application to last-step enzymatic [18F]fluorination for PET imaging by Phillip T. Lowe, Sergio Dall'Angelo, Thea Mulder-Krieger, Adriaan P. IJzerman, Matteo Zanda, David O'Hagan

    Published 2017
    “…Reported herein are the design, synthesis and evaluation of two new 5′-fluorodeoxy-adenosine (FDA)-based receptor agonists (FDA-PP1 and FDA-PP2), each substituted at the C-2 position with a terminally functionalised ethynyl unit. …”
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    Gradient biomimetic platforms for neurogenesis studies by Laurissa Havins, Andrew Capel, Steven Christie, Mark Lewis, Paul Roach

    Published 2022
    “…This focus is targeted towards an urgent need for the diseases that currently have no cure, e.g. Parkinson’s disease. Differentiation studies carried out using traditional 2D cell culture techniques are designed using biological signals and morphogens known to be important for neurogenesis in vivo. …”
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