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    Real time image processing based on-line feedback control system for cooling batch crystallization by Akos Borsos, Botond Szilagyi, Serban P. Agachi, Zoltan Nagy

    Published 2017
    “…The direct nucleation control (DNC) is a process analytical technique (PAT) based model free feedback control strategy for batch and continuous crystallization processes, which has been successfully applied in numerous cases. …”
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  6. 6

    Strategic feedback control of pharmaceutical crystallization systems by Ali N. Saleemi

    Published 2011
    “…Chemometrics is an integral part of PAT, and can provide valuable information about the system. …”
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  7. 7

    Process-analytical technology-based approaches for the monitoring and control of size and polymorphic form in pharmaceutical crystallisation processes by Mohd R. Abu Bakar

    Published 2010
    “…Driven by the United States Food and Drug Administration s (FDA) Process Analytical Technology (PAT) initiative and the Quality-by-Design (QbD) concept, the development of control approaches, which can improve the manufacturing of products with desired properties, has become of significant interest. …”
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  8. 8

    Iterative learning control of crystallisation systems by Nahid Sanzida

    Published 2014
    “…In addition, there is a growing demand for modelling and control tools based on process operating data. …”
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  9. 9

    Modelling and control of crystal purity, size and shape distributions in crystallization processes by Akos Borsos

    Published 2017
    “…Process analytical technology (PAT) brings numerous new methods and opportunities in the process analytics and real time process monitoring systems, which can be integrated into the control algorithm and provide high level optimal control strategies as well as deeper understanding of the process. …”
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  10. 10

    Protein crystallisation using the gas bubble as a soft template by Wenqing Tian

    Published 2023
    “…The protein crystallisation at the gas-liquid interface was hypothesised to be a combination effect of adsorption and heterogeneous nucleation, reducing the free energy required for nucleation and promoting the nucleation of proteins. …”
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