Spectasterols, Aromatic Ergosterols with 6/6/6/5/5, 6/6/6/6, and 6/6/6/5 Ring Systems from Aspergillus spectabilis

Spectasterols A–E (1–5), aromatic ergosterols with unique ring systems, were isolated from Aspergillus spectabilis. Compounds 1 and 2 possess a 6/6/6/5/5 ring system with an additional cyclopentene, while 3 and 4 have an uncommon 6/6/6/6 ring system generated by the D-ring expansion via 1,2-alkyl sh...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 2023-06, Vol.86 (6), p.1385-1391
Main Authors: Wei, Mengsha, Huang, Liping, Li, Qin, Qiao, Xinyi, Zhao, Ziming, Yin, Jie, Fu, Aimin, Guo, Jieru, Hao, Xincai, Gu, Lianghu, Wang, Jianping, Chen, Chunmei, Zhu, Hucheng, Zhang, Yonghui
Format: Article
Language:English
Subjects:
Anti-Inflammatory Agents - pharmacology
Apoptosis
Aspergillus
Aspergillus - metabolism
cell cycle checkpoints
cytotoxicity
Ergosterol - pharmacology
Humans
NF-kappa B - metabolism
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