The proteasome regulator PSME4 drives immune evasion and abrogates anti-tumor immunity in NSCLC

Protein degradation by proteasomes is important for the immune response against tumors. Antigens generated by the proteasome promote immune cell infiltration into tumors and improve tumors’ responses to immunotherapy. For example, immunoproteasomes – a subset of proteasomes induced by inflammatory s...

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Bibliographic Details

Published in:	bioRxiv 2021-10
Main Authors:	Javitt, Aaron, Shmueli, Merav D., Kramer, Matthias P, Kolodziejczyk, Aleksandra A., Cohen, Ivan J., Kamer, Iris, Litchfield, Kevin, Bab-Dinitz, Elizabeta, Zadok, Oranit, Neiens, Vanessa, Ulman, Adi, Radomir, Lihi, Wolf-Levy, Hila, Eisenberg-Lerner, Avital, Kacen, Assaf, Alon, Michal, Rêgo, Ana Toste, Stacher-Priehse, Elvira, Lindner, Michael, Koch, Ina, Bar, Jair, Swanton, Charles, Samuels, Yardena, Levin, Yishai, da Fonseca, Paula C. A., Elinav, Eran, Friedman, Nir, Meiners, Silke, Merbl, Yifat
Format:	Article
Language:	English
Subjects:	Cancer Biology
Citations:	Items that this one cites
Online Access:	Get full text
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