Kartlegging av forekomst og risikofaktorer for ROP ved Ullevål sykehus i perioden 2017-2020

Purpose: To explore occurrence and risk factors of retinopathy of prematurity (ROP) as well as to assess the quality of the Norwegian screening program of ROP. Today’s screening is mostly based on research from other countries with similar population and health care systems. Therefore, we found it i...

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Main Author: Andersen, Emma Prytz Berset
Format: Dissertation
Language:Norwegian
Online Access:Request full text
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Summary:Purpose: To explore occurrence and risk factors of retinopathy of prematurity (ROP) as well as to assess the quality of the Norwegian screening program of ROP. Today’s screening is mostly based on research from other countries with similar population and health care systems. Therefore, we found it interesting to complete the Norwegian ROP register. With this material, we wanted to find whether there is any correlation between gestational age (GA), birth weight (BW), gender, multiplets and development of ROP. In addition to this we wanted to assess whether the Norwegian ROP screening program includes too many infants. Methods: A population-based study of infants screened for ROP at Ullevål Hospital from 2017 to 2020. Data were collected from doctors’ journals and registered in the ROP register. Results and discussion: 223 infants were included in the study, 87 of them developed ROP. During our study, 81 children (44,8%) with GA < 31 weeks developed ROP. As the GA increased, the incidence of ROP decreased. The median GA for those developing ROP was 27+2 weeks with a median BW of 935g, while those without ROP had a median GA of 29+3,5 weeks and median BW of 1317,5 g. Both GA and BW are important risk factors for development of ROP. The incidence of ROP was higher among twins than singletons. There were also gender differences, where the incidence of both prematurity and ROP was higher among boys. All seven who needed ROP treatment were boys, which indicates that boys are at greater risk of developing more severe disease. Conclusion: The Norwegian ROP screening include many children, where few will develop ROP and even less need treatment. ROP examinations may increase the risk of morbidity and require a lot of resources. We therefore suggest reducing today's screening criteria to GA < 31 weeks, and only include infants with GA > 31 weeks who have risk factors of developing ROP.